A clearer cardiovascular aging signal
Published · European Heart Journal 2026

Know what your heart may be trying to tell you.

Understand patterns routine screening may not reveal, while there is still time to ask better questions and take control.

CardioSight brings your existing imaging, labs, and health context into one intuitive Heart Age designed to start a more useful conversation with your care team.

Planned early-access price: $99 per report - educational, not a diagnosis

CardioSight · Heart Age
Illustrative

Heart Age

61

years

Chronological age

52

+9 yrs older

Your heart may be aging faster than you are. CardioSight helps you see it — while there is still time to act.

No new scan or radiation You control your data Delete submitted scans anytime Educational · not a diagnosis

The unseen problem

You may already have the scan. The information inside it may never have been translated.

A chest CT is usually read for the single reason it was ordered. The texture and distribution of fat directly surrounding the thoracic aorta may contain additional information about cardiovascular aging that is not part of a routine read.

That information doesn't disappear. It sits in your imaging, unread and unexplained. CardioSight is built to translate it into something you can understand — a single Heart Age.

How it works

From scattered health data to a Heart Age you can use.

The solution localizes cardiovascular signals in information you already have, places them in context, and turns the result into a report built for a patient-clinician conversation.

Illustrative pipeline - not a real patient scanExisting CT -> segmentation -> heat map -> Heart Age
Peri-aortic fat: current research modelEpicardial + pericardial fat: expandingIntermuscular + subcutaneous fat: expandingAuthorized labs + vitals: clinical context
  1. 01

    Existing chest CT

    Start from a chest CT or coronary calcium scan you already have. No new imaging, no radiation.

  2. 02

    Heart & aorta segmentation

    The pipeline identifies the heart and thoracic aorta as anatomical landmarks for the analysis.

  3. 03

    Fat depot mapping

    Peri-aortic fat is the current research signal; epicardial, pericardial, intermuscular, and subcutaneous depots expand the map.

  4. 04

    Radiomic feature extraction

    Volume, attenuation, and texture features are extracted from the peri-aortic fat.

  5. 05

    Heart Age

    The localized imaging phenotype is translated into one intuitive number and placed in reference-population context.

  6. 06

    Patient report

    Your result, signal map, metrics, and next-step discussion prompts are delivered in a secure portal and printable PDF.

CardioSight imaging insight
Illustrative report

Heart Age

61

years
Accelerated aging pattern

Reference population

Higher than 82 of 100 reference scans

82nd

Imaging insight

The localized peri-aortic tissue signal resembles an older-appearing cardiovascular phenotype in the research model.

This is not a diagnosis or a prediction of a specific event. It is an imaging-derived reason to place the scan in the context of the person's broader cardiovascular health.

Chest CT showing segmented anatomy and peri-aortic fat
Axial chest CTSignal localized
Peri-aortic region

Volume

measured

Spatial burden

Attenuation

measured

Tissue density

Texture

measured

Heterogeneity

31 radiomic features -> validated age model -> Heart Age

What can be done next

See where the signal came from, compare it with a reference population, and review common prevention discussion areas with a clinician.

Explore the full report ->

What you receive

One clear number, explained.

Your report centers on a single Heart Age, the localized CT signal behind it, and a plain-language explanation of what it can and cannot mean.

  • Heart Age. One imaging-derived estimate of how old the cardiovascular tissue phenotype appears.
  • What was analyzed. The volume, attenuation, and texture of fat directly surrounding the thoracic aorta.
  • Plain-language explanation. What the result means, what it doesn't, and what to do next.
  • A prompt to talk to a clinician. Designed to support — not replace — clinical evaluation.
See an example report →

CardioSight report · illustrative

Example

Heart Age

61

years
Accelerated aging pattern

Localized insight

A peri-aortic tissue signal was isolated and translated through the validated age model.

Next: review the result alongside standard cardiovascular risk factors with a clinician.

Illustrative example. Heart Age is an estimate of how old the cardiovascular system appears based on imaging features — not a diagnosis or a prediction of a specific event.

The science

Start with the strongest signal. Expand the map responsibly.

Peri-aortic adipose tissue is the foundation of the current published model. CardioSight measures its volume, attenuation, and texture while developing a broader view across epicardial, pericardial, intermuscular, and subcutaneous fat depots.

Anatomical localization

Heart and aorta segmentation establishes the anatomical landmarks needed to isolate the fat directly surrounding the thoracic aorta.

A mapped adipose phenotype

A 31-feature peri-aortic signature anchors the current Heart Age model. Additional fat depots are an explicitly labeled expansion, not presented as validated today.

Not a diagnosis

Heart Age is educational, imaging-derived information. It is designed to support, not replace, clinical evaluation.

Published multicenter validation

The model was trained in 4,451 scans and externally validated in 44,214 scans across four CT cohorts.

Existing chest CT — illustrative CardioSight pipeline step

Existing chest CT

The scan you already have.

Heart & aorta segmented — illustrative CardioSight pipeline step

Heart & aorta segmented

The pipeline establishes anatomical landmarks.

Fat compartments segmented — illustrative CardioSight pipeline step

Fat compartments segmented

Peri-aortic fat is isolated for radiomic analysis.

Primary source

Peri-aortic fat to assess cardiovascular aging using an AI-driven radiomic biomarker

Lebowitz M, Modanwal G, Singh A, et al. European Heart Journal, 2026. A peri-aortic adipose radiomic signature was trained in 4,451 scans and externally validated in 44,214 scans across four CT cohorts, estimating cardiovascular age with a mean absolute error of 2.7 years in the primary external validation.

doi.org/10.1093/eurheartj/ehag498 →

Your journey

From curiosity to a clear result.

  1. 01

    Enter your information

    Create a secure account and tell us where your records live.

  2. 02

    Connect your portal

    Choose your health system or MyChart portal so the right record source is identified.

  3. 03

    Choose how we get the images

    Upload the study yourself or authorize CardioSight to request it from the provider.

  4. 04

    We build the signal map

    Imaging is localized, measured, and placed alongside authorized labs and vitals.

  5. 05

    Receive and use the report

    Open your Heart Age in the portal, save a PDF, and bring it to a clinician conversation.

Early access uses direct upload or an authorized records request. Direct portal and automated imaging-network retrieval are planned integrations and will only be described as live when they are available.

For health systems

Keep quiet risk from slipping through the cracks.

Give radiology and cardiology teams a way to surface an aging signal from CT studies already moving through care, then route appropriate patients into a follow-up pathway.

  • Confidence beyond the routine read

    Help the care team see a cardiovascular-aging pattern that may not be visible in standard risk fields.

  • Fewer missed follow-up opportunities

    Create a consistent route from an imaging signal to an appropriate clinician review queue.

  • A workflow clinicians can use

    Return Heart Age inside the PACS and health-system workflow rather than in another disconnected portal.

  • A measurable service line

    Track eligible studies, completed analyses, patient outreach, and downstream follow-up without promising a diagnosis.

Why we're building CardioSight

Information that already exists should reach the person it's about.

Millions of people carry a chest CT in their records that contains signal about how their cardiovascular system is aging — signal that is rarely extracted, explained, or connected to prevention. We started CardioSight to close that gap.

CardioSight is led by Mendy Lebowitz, first author of the peri-aortic Cardiovascular Age study published in the European Heart Journal (2026), working with a team of imaging-AI researchers and clinicians.

Privacy by design

Your images stay yours.

We treat your imaging as sensitive health information, we don't sell your data, and you can delete submitted scan and report data from your account.

  • Encrypted in transit and at rest

    Data moves over modern TLS connections and is encrypted at rest by our infrastructure provider.

  • You control retention

    Delete your submitted scan and report data in your account, or contact us to request full account deletion.

  • Granular, revocable consent

    Separate consent for records retrieval, analysis, and any research use — revocable at any time.

  • No ad trackers on health pages

    We don't run advertising pixels on pages that touch your health information.

FAQ

Common questions, straight answers.

I already had a chest CT — is there cardiovascular information in it I never heard about?
It may. A chest CT is usually read for the reason it was ordered. CardioSight analyzes radiomic patterns in the fat directly surrounding the thoracic aorta that are not part of a routine read.
Can my cardiovascular system look older or younger than my actual age?
Yes. Heart Age is an imaging-derived estimate of how old your cardiovascular system appears relative to a research reference population.
Do I need another scan or more radiation?
No. CardioSight uses a chest CT or coronary calcium scan you already have — no new imaging and no additional radiation.
What does the AI analyze?
It uses the heart and aorta as anatomical landmarks, segments the fat directly surrounding the thoracic aorta, and extracts volume, attenuation, and texture features that are translated into one Heart Age.
Is Heart Age a diagnosis or a prediction that I'll have a heart attack?
No. It is educational, imaging-derived information — not a diagnosis, not a risk percentage, and not a prediction of a specific event. It's designed to support a conversation with a clinician.
What if my Heart Age looks accelerated?
It's a prompt to look closer, not a verdict. Discuss the result with a qualified healthcare professional who can put it in the context of your full health picture.
Will a clinician review my result?
An optional clinician consultation is being developed. It is not part of the standard result today, and we don't advertise mandatory clinician review.
How do you get my scan, and how do I receive the report?
You upload a scan you have, or we help you request it from your imaging center. Your result is delivered by email and a secure portal. Automated health-record connections are planned, not yet live.
Who can access my imaging and health information?
Only the people and systems needed to produce your result. We don't sell your data, we use granular revocable consent, and you can delete submitted scan and report data from your account.
Is CardioSight FDA-cleared?
No. CardioSight is not FDA-cleared or approved. It provides educational, imaging-derived information and is not a substitute for professional medical evaluation.

Get a clearer signal while there is still time to act on it.

Join early access, tell us where your records live, and choose whether to upload your CT or authorize us to request it.